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About Dr Gareth Nye

Gareth started his career in academia by studying for a BSc in Physiology at The University of Liverpool. He continued his training and development at The Centre For Integrated Research Into Musculoskeletal Ageing in Liverpool, where he studied for a PhD in musculoskeletal pathophysiology. His PhD focused on understanding how the musculoskeletal system ages in an integrated way and looked at interventions to prevent and reverse the damage – in particular, reactive oxygen species. Gareth continued his research career at the University of Manchester and applied the techniques he developed during his PhD to investigate how and why some babies do not reach their genetic growth potential.

Gareth joined the University of Chester in 2019 as a lecturer of physiology and is programme leader for BMedSci Medical Science. He is also a mental health first aider within Chester Medical School.

Teaching

Gareth has previous experience teaching on undergraduate and postgraduate physiology programmes and supervision of undergraduate and postgraduate dissertation students. His areas of teaching include cell biology, physiology and pathophysiology/disease.

Research

Gareth’s research focuses on conditions affecting the maternal and fetal environment during pregnancy and how that can influence life post pregnancy.

Published Work

Erlich, A., G. A. Nye, P. Brownbill, O. E. Jensen & I. L. Chernyavsky (2019) Quantifying the impact of tissue metabolism on solute transport in feto-placental microvascular networks. Interface Focus, 9, 20190021.

Slator, P., R. Aughwane, G. Cade, D. Taylor, A. L. David, R. Lewis, E. Jauniaux, A. Desjardins, L. J. Salomon, A. E. Millischer, V. Tsatsaris, M. Rutherford, E. D. Johnstone, A. Melbourne et al.  Placenta Imaging Workshop 2018 report: Multiscale and multimodal approaches. Placenta. Published online Oct 2018. (IF 2.434)

GA Nye, E Ingram, ED Johnstone, OE Jensenm H Schneider, RM Lewis, IL Chernyavsky and P Brownbill. Human placental oxygenation in late gestation: experimental and theoretical approaches. Journal of Physiology. Dec 2018. (IF 4.739)

Acharya G, Aplin J, Brownbill P, Bulmer J, Burton G, Chamley L, Chernyavsky I, Clark A, Collins S, Cottrell E, Dilworth M, Elad D, Filoche M, Hannan N, Heazell AEP, Jensen O, Johnstone ED, Leach L, Lewis R, Morgan T, Myers J, Nye G, Oyen M, Salafia C, Schneider H, O'Tierney-Ginn P. IFPA meeting 2017 workshop report: Clinical placentology, 3D structure-based modeling of placental function, placental bed, and treating placental dysfunction. Placenta. Dec 2017 64 Suppl 1:S4-S8 (IF 2.434)

GK Sakellariou, B McDonagh, H Porter, II Giakoumaki, KE Earl, GA Nye, A Vasilaki, SV Brooks, A Richardson, H Van Remmen, A McArdle and MJ Jackson. Comparison of whole body SOD1 knockout with muscle specific SOD1 knockout mice reveals a role for nerve redox signaling in regulation of degenerative pathways in skeletal muscle. Antioxidants & Redox Signalling. 2017. 28(4):275-95 (IF 7.407)

GA Nye, GK Sakellariou, H Degens, AP Lightfoot. Muscling in on mitochondrial sexual dimorphism; role of mitochondrial dimorphism in skeletal muscle health and disease. Clinical Science (London). Aug 2017.  131(15):1919-22 (IF 5.629)GK Sakellariou, T Pearson, AP Lightfoot, GA Nye, N Wells, II Giakoumaki, RD Griffiths, MJ Jackson and A McArdle. Mitochondrial redox homeostasis regulates organelle integrity and function but is not implicated in muscle aging. Scientific Reports. Sept 2016. 2045-2322 (IF 4.122)

GK Sakellariou, T Pearson, AP Lightfoot, GA Nye, N Wells, II Giakoumaki, RD Griffiths, MJ Jackson and A McArdle. Long-term administration of mitochondria-targeted antioxidant MitoQ exacerbates age‐related oxidative damage, impairs respiration and induces functional deficits in aging skeletal muscle. FASEB J. Nov 2016. 30(11):3771-85 (IF 5.498)

AP Lightfoot, GK Sakellariou, GA Nye, F McArdle, MJ Jackson, RD Griffiths, A McArdle. SS-31 attenuates TNF-α induced cytokine release from C2C12 myotubes, Redox Biology. Dec 2015. 28(1) (IF 7.126)

AP Lightfoot, R McCormick, GA Nye & A McArdle. Mechanisms of skeletal muscle ageing; Avenues for therapeutic intervention, Curr. Op. Pharm. Jun 2014. 16:116-21 (IF 6.313)

Qualifications

BSc (Hons) Physiology, University of Liverpool, 2012

PhD, University of Liverpool, 2016