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Prince Asiamah.

Prince Obeng Asiamah, a PhD student at the Chester Medical School, is currently doing research into diabetes. He wants healthy adults, as well as those with type two diabetes mellitus (T2DM,) to help him find out how the disease develops in humans.

Prince, from London, has been studying at the Chester Medical School. He said: “We’re looking to find out if the levels of lysophosphatidic acid – a protein found in the blood – is higher in type two diabetic patients compared to healthy individuals.

“Lysophosphatidic acid is important because it plays an important signalling role in multiple biological processes. Recent research has shown it plays an important role in fat accumulation and we want to investigate this process in type two diabetics.”

He added: “Changes that are known to occur in type two diabetic patients, such as changes in urine composition and blood glucose, will also be compared to the blood levels of the lysophosphatidic acid protein.”

The research is being undertaken on healthy male and female adults and T2DM patients between the ages of 18 to 65.

The study hopes to uncover aspects of how type two diabetes develops in humans.

Prince explained: “We’ll do this by comparing lysophosphatidic acid concentration in normal adults with that in T2DM patients to see if there are any clinical implications.”

Participants in the study will be required to attend a clinic at the Chester Medical School for one 20-minute appointment, where they will have their body composition, weight, and waist-size assessed. They will also be required to give a fasting blood sample and have a urine test at the end of the session.

Prince said: “It’s just a one-time clinic – volunteers won’t have to come back, so we won’t be taking up too much of their time. Participants will also get information about muscle mass, fats and obesity level during this clinic.”

Volunteers will be asked to fill in a pre-screening questionnaire to determine their eligibility. The deadline for applications is June 2020.

For more information, please contact Prince Asiamah by email at dialpa@chester.ac.uk

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